This report presents the findings of an Institute for Work & Health (IWH) project focused on musculoskeletal injury (MSI) prevention and program implementation in Newfoundland and Labrador. The objective of the project was to collect data about current MSI practices in the province (practice evidence) and synthesize it with evidence from the scientific literature (research evidence). The project also sought to close the gap in the literature between MSI prevention practices and implementation in workplaces. The project culminated in a lay-friendly resource that aims to support the implementation of effective and creative MSI prevention programs and practices in Newfoundland and Labrador.