There are 60 well-established workplace carcinogens identified by the International Agency for Research on Cancer. But there are over 100 industrial chemicals (and other agents) that are suspected to cause cancer. Canada lacks any rapid, low-cost means to assess whether exposures, occupations or industries pose an increased risk. In this plenary, the director of the Occupational Cancer Research Centre shares two projects currently being undertaken to establish alternative models for occupational cancer surveillance in this country. If successful, these projects will create two, alternative platforms for the surveillance of occupational cancer in Canada.