Understanding the relationship between osteoarthritis and work: a systematic review
Reasons for the study
Arthritis is among the most prevalent chronic health problems in Canada. It is estimated to affect more than 4.4 million people, which makes it the leading cause of physical disability in Canadian adults. Although often thought of as a disease of aging, about 60 per cent of people with arthritis are under age 65, with most being in their prime earning years (ages 45+). As a result, costs for arthritis are high. In 2000, the estimated burden of the disease in Canada was $6.4 billion per year, with two thirds ($4.3 billion) being indirect costs largely related to productivity losses and long-term disability. Osteoarthritis (OA) is the most common type of arthritis and ranks among the top ten causes of disability world-wide. Of increasing interest are personal and environmental factors that may contribute to the development of OA or aggravate its trajectory over time, particularly the role of occupational activities. This systemic review examined the research evidence to see if there is an association between OA and work.
Objectives of the study
- To examine the current literature to ascertain the level and quality of evidence for a causal relationship between work-related activities/exposures and the development of OA, including the type of work activities potentially associated with OA and whether the amount of activity matters
- To examine factors that may independently relate to the development of OA or that may modify or mediate the relationship between work activities and trajectory of OA in terms of sustaining work
Related research summaries
- Work activities and the development of osteoarthritis in men and women. Sharing Best Evidence: Institute for Work & Health, June 2020.
Related scientific publications
- Gignac MA, Irvin E, Cullen KL, Van Eerd D, Beaton DE, Mahood Q, McLeod CB, Backman CL. Men and women's occupational activities and the risk of developing osteoarthritis of the knee, hip, or hands: a systematic review and recommendations for future research. Arthritis Care and Research. 2020;72(3):378-396. doi:10.1002/acr.23855. (Open access)
Collaborators and partners
The Arthritis Society